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Position title: Post-Doctoral Associate
Organization: Laboratory of Dr Douglas Feinstein, University of Illinois
Location: Chicago, Illinois
This Post-Doctoral Associate will conduct research on studies to induce remyelination in a mouse model of Multiple Sclerosis (MS) in the laboratory of Dr Douglas Feinstein at the University of Illinois in Chicago, Illinois. The postdoctoral researcher will collaborate with Dr. Feinstein and other laboratory members to design, perform, and analyze experiments using in vitro and in vivo experimental approaches. This project involves causing loss of myelin in the CNS by treating mice with the demyelinating agent Cuprizone (CPZ). Following treatment, mice will be administered Lanthionine Ketimine Ester (LKE) which we showed induces remyelination (see Dupree et al. (2022) ASN NEURO). The postdoctoral researcher will perform studies to optimize the timing and dosage of LKE, and will test if remyelination is maintained after LKE is halted. Assays will include immunocytochemistry (ICC), qPCR, and electron microscopy. In vitro studies will be done using primary cultures of oligodendrocytes (OLGs), to screen newer LKE derivatives for higher potency, and will include assays for markers of survival and maturation using qPCR and IHC. The post doctoral associate will examine the role of the protein CRMP2, a target of LKE, using the Cre-Lox approach to generate mice with conditional knockout of CRMP2 from OLGs; and pharmacokinetic analyses to measure LKE accumulation in tissue. The post doctoral associate will carry out behavior studies to determine if LKE reduces deficits due to the loss of myelin.
The candidate should have previous experience working with mouse models of neurodegenerative diseases. The candidate should also have experience with some or all of the above methods including transcardial perfusion of mice, IHC, RNA isolation and qPCR, mouse genotyping, primary cell culture, and behavior analyses including open field testing, novel object recognition, and rotarod.
The studies are supported by a VA Merit grant from the Department of Veterans Affairs, and by the National Multiple Sclerosis Society, and funds are available for up to 3 years. The salary level will follow current NIH recommendations based on number of years of previous post-doctoral experience.
If interested, please send a recent c.v. with at least 2 references listed. For more information or with any questions please contact Dr Feinstein at firstname.lastname@example.org.
Position title: Assistant Professor in Chemistry
Organization: Bowdoin College
Location: Brunswick, ME
Summary of position:
Bowdoin College’s Department of Chemistry invites applications for a tenure-track faculty appointment in chemical biology, biochemistry or neurochemistry at the assistant professor level, beginning July 1, 2023. A PhD in biochemistry, chemistry or a related field is expected by the date of appointment. We are interested in candidates able to teach introductory chemistry and biochemistry who bring expertise that connects with existing interdisciplinary programs at the college (such as biochemistry, neuroscience, digital and computational studies, or environmental studies), strengthen one or more of the interdisciplinary tracks through our major (e.g. the neurochemical track), or bring new knowledge and skills (e.g. a focus on bioinformatics).
The successful applicant will join a supportive chemistry department comprised of nine faculty members (including five women and two faculty of color), six laboratory instructors, an instrumentation specialist, and a departmental coordinator. The teaching load is three courses per year and will include responsibility for an intermediate course in the successful candidate’s area of expertise, with periodic offering of an intermediate level biochemistry course; an introductory chemistry course; and an advanced course related to the candidate’s research strengths or a non-majors science course. Full-time laboratory instructor support is provided for introductory and intermediate level courses.
Bowdoin requires its faculty to have a promise of long-term successful research and a strong commitment to inclusive excellence in their teaching. (For a description of inclusive excellence, please consult the following resource: Williams, et. al., Toward a Model of Inclusive Excellence). The successful candidate must possess a strong commitment to undergraduate liberal arts education and demonstrate the potential to develop a funded, active, and productive research program that involves undergraduates.
The Bowdoin community warmly welcomes people of all backgrounds. We encourage applications from candidates committed to the instruction and support of a diverse student population and those who will enrich and contribute to the College’s multifaceted diversity. We especially encourage people from historically excluded groups to apply. We recognize that recruiting and retaining faculty may involve considerations of spouses and domestic partners. To that end, where possible, the College will attempt to accommodate and respond creatively to the needs of partners and spouses of members of the faculty.
Bowdoin College offers opportunities for professional development, a fully funded, year-long junior sabbatical leave (after three years of teaching and successful reappointment), and regular, generously funded, post-tenure sabbaticals. Support for teaching, grant-writing, digital initiatives, computing software, and community partnerships in courses is readily available to all faculty. The college also offers robust programming and resources for establishing and enhancing mentoring networks.
Contact: Rick Broene
Dates: August 19th – September 16th, 2022
2 Postdoctoral scholar positions with competitive salaries and benefits are available immediately in Dr. Tiwari-Woodruff Lab at the School of Medicine, University of California, Riverside. The primary focus of our research is understanding demyelination and neurodegeneration in multiple sclerosis (MS). The lab is actively investigating therapeutic agents that have immunomodulatory and remyelinating properties to induce recovery and repair. Post-doctoral scholar positions are immediately present for two funded projects
i) investigate Purkinje cell mitochondria dysfunction in demyelinating cerebellum (neuroscience and/ immunology or electrophysiology background)
ii) investigate the initiation of seizure and involvement of inhibitory neurons and astrocyte gap junctions in chronically demyelinated mouse model of multiple sclerosis (required brain slice electrophysiology background).
For additional information about ongoing and reference research, please reach out to Dr. Tiwari- Woodruff, email@example.com
Tiwari-Woodruff lab use animal models, immunology, electrophysiology, molecular biology, and biochemistry approaches. Candidates should have strong neuroscience, neuroimmunology or electrophysiology experience. Candidates should have a doctoral degree in neuroscience, immunology, biochemistry, physiology, or related field. We welcome and strongly support scientists with diverse backgrounds who are energetic and highly motivated for career advancement in academia or industry. Postdoctoral salary is commensurate upon qualifications and 2-step higher than NIH NRSA stipends (https://graduate.ucr.edu/postdoctoral-studies). University of California also offers competitive salary and benefit for staff scientists.
A member of the world’s most prestigious public university system, UC Riverside is an institution powered by an entrepreneurial spirit, a record of innovation and results, and a commitment to excellence and collaboration across disciplines. UC Riverside has a vibrant research environment (including 2 Nobel Laureates and more than a dozen of National Academies members). Our lab is housed in the state-of-the-art Multidisciplinary Research Building, UC Riverside’s newest and largest research building. The campus is also located in a prime position close to other universities, research institutes, and biotech industries present in Southern California.
Riverside is a wonderful place to live, providing ample cultural and entertainment opportunities in a safe and comfortable community with affordable housing and living expenses. Riverside is about an hour away from beautiful beaches and ski slopes. The city offers all the cultural advantages of any U.S. city, together with the amazing all-year-round weather of sunny Southern California without the living costs.
Preference will be given to candidates with research experience in mouse immunology, pathology, and electrophysiology. Ability to work both independently and cooperatively within a team is essential.
Applicants should send a CV, a brief research statement, and the names/contact information of three references to Dr. Tiwari-Woodruff via email: firstname.lastname@example.org
UNIVERSITY OF NEBRASKA MEDICAL CENTER- Omaha, Nebraska
A NIH-funded postdoctoral position is available in the laboratory of Dr. Tammy Kielian in the Department of Pathology and Microbiology, University of Nebraska Medical Center (UNMC) in Omaha, Nebraska (https://www.unmc.edu/pathology/faculty/bios/kielian.html). The candidate will direct independent projects related to the role of innate and adaptive immunity in host defense against Staphylococcus aureus using a mouse model of S. aureus craniotomy infection as well as translational research with clinical specimens from patients with craniotomy infections. Our laboratory utilizes numerous tools to explore host-pathogen crosstalk, including single cell RNA-seq, epigenetic platforms, and transposon sequencing. Twitter: @KielianLab
UNMC has a vibrant research and medical community within the growing and affordable city of Omaha, Nebraska. The Department of Pathology and Microbiology has over 60 faculty members, nearly 100 graduate students, postdoctoral fellows, and residents working in modern, well-equipped labs with state-of-the-art facilities. The Staphylococcal Research Group at UNMC (https://www.unmc.edu/pathology/csr/) offers a collaborative multi-disciplinary environment for the study of staphylococcal infections.
The successful candidate should possess a PhD in neuroimmunology or a related background and have excellent written and oral communication skills. Salary will be commensurate with experience.
Interested persons should send a Curriculum vitae, summary of research experience and interests, and contact information of three references to Tammy Kielian, PhD, via an online application through the University of Nebraska Medical Center employment website at https://unmc.peopleadmin.com/postings/66883. Applications will be reviewed as they are received and will continue until the position is filled.
Organization: Michigan State University
Summary of position
The Gulbransen and Jackson labs use advanced cellular imaging and genetic approaches to study interactions between neurons and non-neuronal cells in the periphery. Major techniques used in these studies include network- and cellular-level calcium imaging with GCaMPs, selective cell stimulation using chemogenetics, cell labeling assays, fluorescent reporter systems, RNA sequencing, and physiological assays of function.
The successful candidates will be expected to conduct experiments aimed at understanding the neurohumoral regulation of perivascular adipose tissue, collect and analyze data from these experiments, and report the results of these studies at scientific meetings and in publications (70% effort). The successful candidate will also be expected to oversee the daily operations of a microscopy core facility which houses a Zeiss LSM 880 NL microscope with Airyscan detectors, train users in the use of this microscope; train and assist with image analysis; and help facilitate collaborative research effort using this system (30% effort). There will also be opportunities to participate in professional development programs and to write and submit grants and career development awards.
Qualified candidates must have a Ph.D. in Neuroscience, Physiology, Pharmacology, Physics, Immunology, or a related field. Candidates must also have at minimum of 2 years of postdoctoral training in live cell imaging using confocal, 2- or multiphoton imaging, or similar methods. Candidates must have demonstrated experience in image analysis and processing and should have a track record of research in, or complementary to vascular physiology or pharmacology, neurobiology, immunology or related fields. The candidate must have excellent oral and written communication skills, and to be willing to work with a diverse group of investigators.
This position is a 12-month fixed term appointment with opportunity for renewal based on performance and funding.
Interested candidates should submit the following application materials: 1) a letter of intent outlining their qualifications and career objectives, 2) curriculum vitae, 3) three letters of reference. Inquiries should be directed to Dr. Brian Gulbransen at email@example.com or to Dr. William Jackson at firstname.lastname@example.org. Formal applications should be submitted through the MSU applicant portal:
Review of applications will begin immediately and continue until the position is filled.
Contact information: Inquiries should be directed to Dr. Brian Gulbransen at email@example.com or to Dr. William Jackson at firstname.lastname@example.org
Postdoctoral positions are available for 2-3 years in the laboratory of Dr. Munjal Acharya funded by NIH, California Institute of Regenerative Medicine (CIRM) and the American Cancer Society (ACS). Salary will be commensurate with experience.
The scholar will be responsible for investigating regenerative strategies to remediate radiation- or chemo-therapy-related brain injury (chemobrain) and cognitive dysfunction. Additional projects will involve characterizing the impact of gliosis (microglial and astrocytic activation), neuroinflammation and CNS complement cascade activation on brain function. Our laboratory employs gene silencing, transgenic, stem cell-based and pharmacological approaches to study neurobiological mechanisms and regenerative strategies to ameliorate neuroinflammation and cognitive impairments.
Successful candidates will have an excellent track record and be highly motivated scientist who can carry out independent experiments and work well with a team. The successful candidate will play a critical role in contributing to execution of the overall aims of the project and the analysis and preparation of the data for presentation in scientific meetings and pee-reviewed publications.
Send CV with the names and addresses of three references (please do not solicit letters) to:Dr. Munjal Acharya email@example.com
To apply go to https://recruit.ap.uci.edu/JPF07131
Send the required information below to firstname.lastname@example.org.
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