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Saturday Mar 19, 20169:00 am - 12:00 pmGrand Hyatt Denver
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Glutamate, which is present in the vast majority of synapses in the brain, may be the most important yet least understood neurotransmitter in the human brain. It is becoming apparent that glutamate signaling is a product of an elaborate network of release mechanisms, transporters, and receptors expressed by neurons and astrocytes. However, a dearth of knowledge exists regarding the nature of neuronal-astrocytic interactions that regulate excitatory signaling in normal and diseased states. In this session, Drs. Araque, Dulles, Baker, and Berg will present novel findings illustrating diverse ways and means in which these cells interact in order to regulate excitatory signaling. Followed by Short Talks from Student/Postdoc submitted abstracts. 9:00 AM - 12:00 PM PMW01: Abcam Workshop & Networking LunchPROBING OUTSIDE THE SYNAPSE: ASTROCYTE-NEURON REGULATION OF EXCITATORY SIGNALING
Chair: David Baker, PhD PMW01-01 - Astrocyte-Neuron Networks Regulate Glutamate to Influence Basal Ganglia Output Pathway Keynote: Alfonso Araque, PhD; University Minnosota Speakers: Darwin Berg, PhD; UC San Diego Chris Dulla, PhD; Tufts University |
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Pre-Meeting Symposium& WorkshopHosted by
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Saturday Mar 19, 20161:00 pm - 6:30 pmGrand Hyatt Denver
Symposium: No Charge / Workshop: $10 Limited Seating - Register in Advance to confirm your space |
The Allen Institute for Brain Science is now in its second decade and has launched an ambitious program aimed at understanding how the brain receives, processes and perceives vision. To do this, we are combining new high-throughput technology development in functional imaging and connectomics, with single-cell RNASeq and complex 3-dimensional morphological analysis and mathematical modeling, to identify the unique molecular and behavioral signatures of distinct cell phenotypes and circuits in the brain. In the symposium, we will present early data from some of the newer projects emerging from this new direction at the institute – all of which are being scaled up to be publicly available.
1:00 PM - 3:00 PM PMW02: Allen Institute SymposiumFROM SINGLE CELL TRANSCRIPTOMES TO FUNCTIONAL CIRCUITS: NEW FINDINGS FROM THE ALLEN INSTITUTE FOR BRAIN SCIENCE FRONTLINE
PMW02-01 - Mapping Cortical Areas in GCaMP6 Reporter Mice with Widefield Imaging PMW02-02 - Adult Cortical Cell Taxonomy by Single Cell Transcriptomics 3:00 PM - 3:30 PM Coffee BreakIn the workshop, we will present an interactive hands-on guide to how individuals can access and use both our established large-scale gene expression datasets, and emerging datasets in mouse, human and non-human primate. Aimed at putting all of the Allen Institute data and analysis tools in the hands of all attendees, we hope to also use feedback from attendees to keep improving data and tool access for the benefit of the neuroscience community. 3:30 PM - 6:30 PM PMW03: Allen Institute Workshop - $10 Registration
HANDS-ON WORKSHOP: NAVIGATING THE ALLEN BRAIN ATLAS RESOURCES    Chair: Jane Roskams, PhD Terri Gilbert, PhD - Allen Institute for Brain Science |
