Louis Sokoloff, PhD
October 14, 1921 - July 30th, 2015
Dr. Sokoloff, past president (1977-1979) of the American Society for Neurochemistry, died on July 30th 2015 at the age of 93. Born in South Philadelphia, Dr. Sokoloff received a bachelor’s degree in 1943 and a medical degree in 1946 both from the University of Pennsylvania. After a psychiatry residency, Louis Sokoloff began his scientific career as a student of Seymour Kety studying cerebral circulation and metabolism. In 1953 he became a member and then headed the Section on Cerebral Metabolism in the Laboratory of Neurochemistry at the National Institute of Mental Health, where he stayed until retirement in 2004. During this time he developed the 2-deoxyglucose technique for quantitative measurement of regional glucose metabolism in the brain. This led directly to the invention of revolutionary noninvasive methods for functional imaging of the human brain. Over the course of his distinguished and long career in science, Dr. Sokoloff received a number of prestigious awards including the P. O. Schmitt Award (1980), the Albert Lasker Clinical Medical Research Award (1981), the Karl Spencer Lashley Award (1987, American Philosophical Society), and the U.S. National Academy of Sciences Award in the Neurosciences (1988), just to name a few.
GERARD M. LEHRER, MD
Gerard Lehrer, known as Jerry to his friends and colleagues, passed away Friday, April 12, 2013, after choking on apple juice, less than 36 hours following an extraordinary repair of an aneurysm at El Camino Hospital, Mountain View, California. Upon his self diagnosis of a rare dissection of the aorta, during a visit to an Emergency Room, eight days earlier, in Monterey, CA, he was treated medically, prior to his transfer to El Camino for endovascular stent graft procedure.
A graduate of the Bronx High School of Science; Phi Beta Kappa graduate of and Pell Medal recipient, City College of New York; research assistant, Columbia University College of Physicians and Surgeons; New York University School of Medicine; Instructor and Special Fellow in Neurochemistry, Washington University School of Medicine; Jerry completed residency at Mount Sinai School of Medicine under Morris Bender, becoming one of the youngest full Professors on faculty.
A scientist, Director of the Division of Neurochemistry and Neuroscience training program, Mount Sinai School of Medicine, New York City, Jerry pioneered research in multiple sclerosis, demyelinating disease, and experimental autoimmune encephalitis. A dedicated physician, beginning practice in 1960 at Mount Sinai Hospital, he was Attending Neurologist, also Co-Director of the Headache Clinic.
A past member of committees at the National Institute of Health, the Advisory Board of National MS Society New York City, and the Board of Directors, Hunger Project, Jerry was a strong supporter of community service. More recent, he served on the Board of the Monterey Chamber Music Workshop and Piano Institute, Berkeley. He considered himself a “citizen of the world.” His many interests included sailing in Maine and the Caribbean, poetry, Goethe, philosophy, the Bible, comparative religion, computer science, electronic gadgets, marzipan, biscotti, and cookies. He was a bargain shopper extraordinaire, reminding others “Anything’s negotiable!”
A Renaissance man, Jerry was a passionate lover of the arts—frequenting performances of classical music, the ballet, and the opera, at Lincoln Center and Central Park. He studied the violin in his youth, practiced performance poetry, directed and performed in theater beginning at City College of New York and soldier shows in the U.S. Special Forces in Austria, and continued in New Jersey, New York City, and in California, at the Forest and Unicorn Theatres. Born May 29, 1927, in Vienna, Austria, son of Charlotte and David Lehrer, he emigrated to New York City with his mother, when he was 11 years old. He was reunited with his father when he was 19 years old.
A senior Fellow of the American Academy of Neurology and American Neurological Association, a founding member of the International Society of Neurochemistry, a member of the New York Academy of Sciences, he authored more than 150 original articles and book chapters on clinical neurology and demyelinating disease. He is survived by his loving wife, Suzanne Macahilig Lehrer; his children, Richard and Alicia Lehrer; and five grandchildren, Max, Harry, Francesca Binder and Nathaniel and Jonathan Lehrer.
Former Senior Staff Neurologist, Veterans Affairs Medical Center, Bronx, NY, not fully retired after relocation to Carmel, CA in 1994, the Palo Alto VA requested Dr. Lehrer’s services at the Livermore, San Jose, then Monterey clinics. Fully “retired” in 1998, he began treatment of disabled MS patients on the Monterey Peninsula, California.
A tribute to Dr. Marie T. Filbin from one who benefited.
On January 15 2014, Distinguished Professor of Biology Marie T. Filbin (1955-2014) died in her native Ireland surrounded by the love and support of her family and friends. Marie suffered in recent years from metastatic breast cancer but as a testament to her courage, commitment, and passion she continued to live her life, to work with her lab and mentor her students until her last days.
Marie was recruited to Hunter College in the early nineties having been the first to attribute a novel function to a key molecule of myelin that would turn out to be the corner stone of her successful career in neural regeneration. This molecule, myelin associated glycoprotein (MAG) was important because of the conceptual breakthrough in how spinal cord regeneration was perceived. Initially, the perception was that axons of neurons “can’t regrow”. However, seminal work by Marie showed that axons can regrow, but that there were substances released after injury that prevented it.
Marie’s scientific work contributed to our understanding of nerve regeneration after spinal cord injury and multiple sclerosis, knowledge that will be crucial for the development of effective therapies to treat these debilitating conditions. Her lab pursued inhibitors of nerve regeneration and activators of axonal growth. She was the first to identify MAG, as a potent inhibitor of nerve regeneration (Mukhopadhyay et al. 1994). Marie’s research subsequently focused on finding ways to overcome this inhibition and promote endogenous regeneration. She identified key intracellular signaling pathways that act as potent activators of axonal growth and could be exploited as therapeutic targets (Cai et al. 2001). While spinal cord regeneration remains daunting, her discoveries have led to promising results in animal models of spinal cord injury (Pearse et al. 2004).
Marie could have achieved great success at any institution, but she enjoyed teaching at Hunter College, a public institution that serves a large population of minority and female students stemming from having been historically an all women’s school. Hunter was previously known for educating two women undergraduates who went on to win the Nobel Prize in Physiology and Medicine (Rosalyn Yalow and Gertrude Elion). Marie was extremely proud of the work carried out by her students and postdocs at Hunter. Leading by example, she demonstrated that a successful scientific career and teaching at a large urban public institution were not incompatible outcomes. “Hunter is a great place for a researcher. My students are wonderful”, she told The New York Times in 2004, and again in 2005 for a profile in Nature Medicine, where she stated that at Hunter she “succeeded beyond her wildest dreams.”
Under Marie’s guidance, sixteen students received their Ph.Ds; and at the time of her death she was the Director of the Specialized Neuroscience Research Program (SNRP) at Hunter. She was also the driving-force behind the Friends of Myelin Club meetings at Hunter Biology Department, which promoted the exchange of ideas and collaborations among scientists working on myelination in the New York area. Marie was very active in numerous scientific organizations and was on the editorial board of a number of major scientific journals, including serving as senior and reviewing editor for the Journal of Neuroscience. During her outstanding career, Marie received many honors including the Javits Investigator Award from NIH, the Ameritec Prize for significant accomplishment towards a cure for paralysis, and she was inducted into the Hall of Fame of the National Multiple Sclerosis Society.
Marie was not only scientifically brilliant, but was also an extraordinary woman with a kind, caring and fun-loving personality. Generous with her time and resources, she instilled in her students and peers the importance of hard work, collaboration and collegiality. She was a devoted advocate for junior faculty and women scientists, mentoring those who like myself started their independent career at Hunter College. It was last October, during the celebration of Marie’s last birthday, that we, a group of junior faculty sharing anecdotes and our favorite “Marie’s story”, asked her about the secret to her success: “Why did I succeed? Because I was able to recognize what was important and what wasn’t” she told us. I think we all agree that Marie’s wise discernment extended not only to her science, but also to how she lived her life. She recognized the importance of “others” and cared deeply about her family, friends, students, trainees and peers. Marie was and will continue to be an inspiration for all of us. We will miss her greatly and will forever look up to her as an example of kindness, bravery and passion for life. Cheers Marie! You will not be forgotten.
Carmen V. Melendez-Vasquez
Cai D, Qiu J, Cao Z, McAtee M, Bregman BS, Filbin MT. 2001. Neuronal cyclic AMP controls the developmental loss in ability of axons to regenerate. The Journal of Neuroscience 21(13):4731-4739.
Mukhopadhyay G, Doherty P, Walsh FS, Crocker PR, Filbin MT. 1994. A novel role for myelin-
Pearse DD, Pereira FC, Marcillo AE, Bates ML, Berrocal YA, Filbin MT, Bunge MB. 2004. cAMP and Schwann cells promote axonal growth and functional recovery after spinal cord injury. Nat Med
Dr. R. Wayne Albers, Ph.D., Chief of Section on Enzyme Chemistry (retired), Laboratory of Neurochemistry in the NINDS, NIH, Bethesda, MD, died September 28, 2013. He was 85 years old and is survived by his former wife, Frances Albers, their children, Gail Morrell, Belinda Caron and Patricia Steinhoff, 6 grandchildren and 8 great grandchildren. Dr. Albers is a world-recognized neuroscientist most noted for his research in the field of membrane cation transport and neuronal excitability in the nervous system. Wayne Albers and physiologist R.L. Post at the University of Pennsylvania performed the principal experiments leading to their now widely-held Albers-Post model for the mechanism of the cation transport enzyme, sodium-potassium-activated ATPase. Dr. Albers was one of the founding co-editors of the comprehensive text, Basic Neurochemistry: Molecular, Cellular and Medical Aspects, first published in 1972, continuing as co-editor for 8 editions, the latest having been published in 2012. This text has evolved as expected over these editions with the emergence of the field of neurochemistry. Wayne’s great knowledge and understanding of the history and of the advancing field of biochemical research were key to development of the text over the past 4 decades. Wayne Albers has been regarded as a pioneering intellect in the field of nervous system biochemistry and whom, through his own research, editing and writing, has helped bring the biochemical perspective to the burgeoning modern field of neuroscience. After receiving his Ph.D. with Oliver Lowry in the Department of Pharmacology at Washington University School of Medicine in 1954, Dr. Albers embarked on a distinguished career of research at the NIH, being a founding investigator, along with Roscoe Brady, in the first Laboratory of Neurochemistry with Donald Tower as Laboratory Chief in the NINCDS.
Dr. Albers was one of the first members of the American Society for Neurochemistry at its inception and served on its Council and on Committees on Publications and Education and on Electronic Publications. He has served as Professor of Biochemistry at George Washington University, faculty member of the NIH Foundation for Advanced Education in the Sciences, and as Associate Editor of the Journal of Neurochemistry and of Experimental Neurology and on the editorial boards of Archives of Biochemistry and Biophysics, Current Topics in Bioenergetics, Journal of Bioenergetics and Biomembranes, Journal of Biological Chemistry, and Metabolic Brain Disease. Wayne Albers was considered a gentleman, an excellent scientific colleague with a keen intellect and friend by all who worked with him and he will be sorely missed, not only by his family, but also by the entire neurochemistry community.
Donations toward a memorial fund for an Albers memorial lecture or research prize may be sent in to American Society for Neurochemistry, 9037 Ron Den Lane, Windermere, FL 34786 Phone: 407-909-9064, Email: firstname.lastname@example.org
George J. Siegel
October 1, 2013
George Hauser, Ph.D., Harvard Professor Emeritus of Psychiatry (Biochemistry), died on September 28, 2012 at age 89 after a long illness. With his passing, we have lost a scientist of immense talent and impressive accomplishment. George was born in Vienna, Austria and only with great difficulty and good fortune was he able to leave that country in 1939 for England and then the United States. His college years were interrupted by World War II, during which he was seriously wounded in France and endured a long recovery. In 2008, he received the Legion d’Honneur from the French government in recognition of his service in the liberation of Normandy.
After finishing his undergraduate studies at The Ohio State University, he became a graduate student in the laboratory of Dr. Manfred Karnovsky at Harvard Medical School and completed his degree in 1955. Thereafter, he was recruited by Dr. Jordi Folch-Pi to the Research Laboratory at McLean Hospital to initiate a program for study of the biochemistry of brain lipids. He remained at McLean for his entire career and served as Interim Director of the Ralph Lowell Laboratories from 1983 to 1993.
Over a 40-year period, George made many distinguished scientific contributions to our knowledge of phospholipid and glycolipid metabolism, with particular emphasis on the role of phosphoinositides in cell signaling. He was a superb colleague and a talented mentor for a succession of trainees who passed through his laboratory. His achievements in neurochemistry were recognized by award of the Austrian Cross of Science and Art, First Class and by being named a Fellow of the Japan Society for the Promotion of Science. George also served on the American Society for Neurochemistry Council, and for many years he was a Deputy Chief Editor of the Journal of Neurochemistry.
George was happily married to Louise (Russo) for more than 50 years. He will be greatly missed by her, as well as his friends and colleagues, not only for his keen mind, but for his old world courtliness, his generosity and his sly sense of humor.
Marjorie Berman Lees, Professor (Emeritus) of Biological Chemistry and Neurology at Harvard Medical School, died January 18, 2012 after a long illness. Marjorie was a truly unique scientist who inspired numerous people throughout her life. She was born in New York in 1923 and graduated from Hunter College. She obtained a Master’s degree at the University of Chicago and then moved with her husband Dr. Sidney Lees to Boston, where she started working with Dr. Jordi Folch-Pi, and decided to obtain a Ph.D. She was supported at Radcliffe College with one of the first NIH-sponsored pre-doctoral fellowships. Her work with Dr. Folch-Pi resulted in the discovery of a novel chloroform-methanol soluble protein in total lipid extracts of the brain, i.e., the myelin proteolipid protein (PLP). She continued studying myelin lipids and the PLP for her entire career. She spent a number of years at Dartmouth Medical School, and then returned to Harvard Medical School, first to the Biological Laboratories at McLean Hospital and later at the Eunice Kennedy Shriver Center for Mental Retardation from 1976 to her retirement.
Marjorie was a remarkable role model for many people. As was noted numerous times at her memorial service, Marjorie was determined. She accomplished whatever she set out to do. She had long-term grant support from the NIH throughout her career. She was very active in the American Society for Neurochemistry, serving on its Council, as Treasurer from 1975-1981 and as President from 1983-1985. She was Editor-in-Chief of the Journal of Neurochemistry from 1986-1989. She sequenced PLP, one of the most difficult, hydrophobic proteins, by brute force using Edman degradation, at a time when there was no DNA cloning and sequencing. When the PLP gene was subsequently isolated and sequenced, her amino acid sequence was beautifully accurate, differing only in some species-specific amino acid residues. She then moved on to investigate the role of PLP in experimental autoimmune encephalomyelitis (EAE). She was among the early investigators in the 1950s who had suggested that PLP could be an encephalitogenic protein, but those observations were overwhelmed for several decades by the extensive data on the encephalogenic potential of the myelin basic protein. Through that time, all mention of the possibility that PLP might play a role was dismissed as likely contamination of the PLP preparation with myelin basic protein. However, Marjorie was determined, and in the 1980s she demonstrated unequivocally that PLP can also be an autoantigen and a potent promoter of EAE. Further studies showed that multiple sclerosis patients have antibodies against PLP as well as numerous other myelin antigens.
For those of us who worked with her, she was an amazing mentor. We all have stories of sitting at her kitchen table or in the living room working on manuscripts. No sending computer files back and forth; one sat and worked over every sentence until it was right, or there was the realization that as beautiful as the sentence was, it didn’t fit and it was gone. She truly cared about her people and about her science. She made major efforts to support her trainees and numerous other junior investigators as they built their careers. Her wonderfully broad smile was a cherished reward for a job well done.
No mention of Marjorie’s life is complete without mention of her family. Marjorie was devoted to her three sons, David, Andy and Elliot, and always felt the loss of her young daughter Constance. She adored her wonderful grandchildren. She and Sid were married for over 60 years. They had a remarkable life together, focused both on their science and their family. A lasting memory for all of us who knew them will be their joy at discussing their science and their family.
Marjorie Lees was a determined, remarkable force of nature, who never worried about whether she could succeed. She just did it. She is truly missed.
It is with appreciation and humility that we celebrate the remarkable life of our good friend and trusted colleague, George Hashim, who passed away in June of 2011. George was truly passionate about his scientific pursuits and enlivened all around him with his quick wit, breadth of knowledge and keenness for a good debate. He contributed much energy, enthusiasm and leadership as a past President of the ASN and for the development of young scientists (as we ourselves were when we first met George). He formed lasting relationships with numerous colleagues throughout the scientific world, and we always suspected that his motive for developing such an extensive network was to travel and indulge with good friends wherever he was! Who wouldn’t enjoy life under those circumstances? Certainly George did.
Halina first met George early in her career when he invited her to present a lecture at Columbia University. She still remembers his graciousness as a host and his sincere interest in her presentation and ideas. Arthur remembers their first meeting in NYC when George fetched him from his hotel in his classic Lincoln convertible for the drive to Columbia University. That image of George leaning out the car window with a wink and a wry smile is indelibly inscribed and epitomized his love of life; it is one of the main reasons we all loved him and enjoyed his company. When the T-cell receptor was finally identified and sequenced in the mid 1980s, our thought was to explore their biological activity, and George, as a global leader in peptide synthesis, was the obvious choice to produce the TCR peptides. In those days, the nuances of peptide synthesis were still being worked out, and the TCR sequences posed some interesting challenges that George and his laboratory were able to overcome. The three of us teamed up to test immunological activity of T-cell receptor peptides from prominently expressed V-region genes and discovered that indeed they could induce regulatory T-cells for treatment of rats with experimental autoimmune encephalomyelitis (EAE). Remarkably, injection of the TCR peptides could not only prevent, but also reverse clinical and histological signs of EAE. George went on to show that immunization of rats with TCR peptides could also increase EAE protective antibodies. The peptide sequences that emerged from this collaboration ultimately became components of a TCR peptide vaccine that was tested with promising results in Phase I/II trials in subjects with multiple sclerosis (MS). This formulation is still in development as a possible therapy for MS. George, we hope you are listening because this story is not yet finished.
Two other of George’s lovable and sometimes laugh-inducing traits were his ability to tell a good story and his insistence that some most recent publication failed to acknowledge his earlier work. Well, the stories were endless but were always told with a positive spin and usually involved jousts with professional competitors (ie. Marian Kies of NIH) or experiences with his good friends (ie. Bernard Haber). To his friends (we count ourselves lucky to be included on this list), he was both gracious and intensely loyal. He was very supportive to us and complimentary about us to other people. He listened carefully to our ideas and could be counted on to give insightful feedback. The effect was inspirational to say the least, and gave us the confidence to believe that we could accomplish almost anything. I’m sure that many others who worked with George must have benefitted in the same way from his unselfish and supportive persona. That is not to say that George was not fiercely competitive about his scientific and personal standing. Truth be told, George did know a lot and published much on a wide range of interesting questions, and it was no surprise to us that many new findings by others had roots in his explorations. With such a fertile career, George likely did think about and pre-sage later discoveries, and we always lent a sympathetic ear to his rumblings.
We and his many other colleagues and friends will miss George a lot.
Arthur A. Vandenbark & Halina Offner
We regret to inform you of the passing of Dr. Alan Boulton, a Past President of the International Society for Neurochemistry (ISN), the American Society for Neurochemistry (ASN) and the Canadian College of Neuropsychopharmacology (CCNP) and a former Chief Editor of the Journal of Neurochemistry, on November 13, 2010 in Nanaimo, British Columbia.
It is with great sadness that we note that Celia Campagnoni died June 17, 2010 in Los Angeles CA. Celia was an important investigator in the myelin field for over 40 years. She collaborated with her husband Tony Campagnoni throughout that time, first at the University of Maryland and later at UCLA, and they were a remarkable team. Celia received her MS at the University of Washington in physical chemistry, and then worked with Dr. Henry Mahler, in whose laboratory she met her future husband. The collaboration of Tony and Celia Campagnoni was extremely important for our understanding of the molecular biology of myelination, and, in particular, novel aspects of the myelin basic protein gene structure and function. Celia was remarkably accurate and precise in her research. She decided in the late 1980’s to screen cDNA libraries for all myelin basic protein related cDNAs and all myelin proteolipid protein cDNAs that could be found. This was a huge undertaking and it provided a treasure trove of new data on the expression of these two myelin genes. Only Celia could have screened for and then catalogued this group of cDNAs and dug into the sequence of the genes, which she had been sequencing herself, to identify a series of previously unidentified exons in these genes. This work led the Campagnoni team to an entirely new research area on a gene that overlaps the myelin basic protein gene, containing both unique and common exons but generating a very different protein.
Celia was quiet and steady, and she kept the Campagnoni lab organized. She was far more interested in generating the data about an exciting question than giving talks on it, and she published over 45 papers and reviews. Celia and Tony were like two peas in a pod: they always traveled together to meetings, attended the same scientific sessions, and checked out the same posters. When Tony would move onto the next poster, Celia would remain behind, ask probing questions about the poster’s content, and then discuss her thoughts with Tony. Many noted that the success of the Campagnoni group came from this wonderful mix of Tony’s communicative style and Celia’s solid research. She was highly respected for her science and for her common sense. She was so highly regarded that she was asked to run for Council of the American Society for Neurochemistry, and with her typical modesty, her first reaction was surprise. She won handily, and was a very valuable councilor for the society.
Celia loved to travel, and she and Tony spent sabbaticals in Europe, visited Asia and South America and truly loved seeing the world. When the Campagnonis entertained, which was always a gala affair, again it was a team effort by the two Campagnonis. Celia delighted in cooking wonderful baked goods and tasty dishes.
Celia was the most loyal of friends, helping many people over the years. She and Tony welcomed many colleagues from around the world to their home and lab for visits, fellowships and sabbaticals. She had a remarkable memory and always wanted to know the latest news about former students and their families. Celia loved her family, her pets, her friends, and her home. Her strength, her wry sense of humor and her intelligence will be greatly missed.
|Joseph Bernsohn, husband of 68 years to Norma, father of Judy Fried-Weinfeld, grandfather of Laurie Fried and Ian Fried, great-grandfather of Maya and Andrew, father- in-law to Arthur and Allison, and step-grandfather to Debbi, David and Jennifer and their families, passed away Sunday at the age of 95. Born in New York City in 1914, Joseph attended Brooklyn College while working and supporting his family during the depression. After receiving his BS degree in biochemistry, Joseph attended the University of Illinois at Champaign-Urbana and received his PhD in nutrition in 1943. In 1950 he started a job as a Career Research Scientist at Hines VA Hospital in Maywood, Illinois, where he stayed until his retirement in 1981. He also held the title of Professor in the Departments of Biochemistry and of Pharmacology at Loyola University Stritch School of Medicine, as well as an adjunct faculty member in the Department of Neurology at Northwestern University School of Medicine. Dr. Bernsohn was a well-established neurochemist, a member of the American Society of Neurochemistry, who had a long- term research interest in the biochemical aspects of neurological disorders. In 1967 he published a seminal paper titled "Aetiology of Multiple Sclerosis (MS)" in the eminent British scientific journal, Nature. There he advanced the novel nutritional hypothesis that deficiencies in the intake of essential fatty acids, in particular, the omega-3 (fish oil- derived) fatty acids, could underlie the development of this disease. It was a very prescient suggestion, given today's burgeoning interest in and knowledge of the beneficial properties of omega-3 fatty acids. Joseph was a true renaissance man with many passions. He and Norma loved their subscription to the Chicago Symphony Orchestra, as well as attending opera, theater and art museums. They travelled extensively around the world and in their retirement spent winters in Ajijic, Mexico. His family and friends know how much he influenced their lives and he is already missed. [FUNERAL INFO] In lieu of flowers, please make a contribution in Joseph's name to the Nicasa Mosaic Arts Project c/o Judy Fried, 1113 Greenwood, Waukegan, IL 60087.|
|Francis N. LeBaron Yarmouthport Resident, formerly of Mashpee
Yarmouthport – Francis Newton LeBaron, 87, died on Monday November 2nd at Cape Cod Hospital. From Framingham, after graduating from M.I.T. he entered the U.S. Navy and served in the North Pacific on the U.S.S. Watts during World War II. Upon leaving the Navy, he obtained a Master’s degree from Boston University and Ph. D. in biochemistry from Harvard. Following a Postdoctoral Fellowship in England and ten years of research in neurochemistry of the brain at McLean Hospital in Belmont, he moved to Albuquerque, New Mexico to set up the U.N.M. Medical School. He eventually served as Chairman of the Biochemistry Department while continuing his research on the aging of the brain. He helped establish the American Society for Neurochemistry, published many research papers, and served on editorial boards of several scientific journals. Following retirement from U.N.M. he lived in Blue Hill, Maine for one year, where he became a certified yacht surveyor.
A dedicated conservationist and avid mountaineer, Fran and his loving wife Margaret, who predeceased him in May of this year, were residents of Cape Cod for the past 25 years. They were deeply involved as volunteers at the Waquoit Bay National Estuarine Research Reserve and the Massachusetts Audubon sanctuaries on the Cape, including setting up two of the world’s first nature trails specifically designed to introduce lichens to the general public. An avid bird watcher, he also volunteered as a warden protecting endangered species on coastal beaches.
He is survived by his son Geoffrey and daughter-in-law Heidi L. Johnson of Williamsburg Massachusetts, brother Kenneth of Sudbury, niece Margaret Pendergast of Sandwich, nephew Michael Pendergast of North Falmouth, and many loving extended family members. To celebrate Fran’s life there will be an informal gathering at Heatherwood in Yarmouthport at 10:30 a.m. on Saturday, November 21st.
In lieu of flowers donations may be made to the McCarthy Care Center of Hospice of Cape Cod or to the Massachusetts Audubon Society.
Dr. Eduardo F. Soto, 81, died on Friday, March 20, 2009. Eduardo obtained both his M.D. (1952) and Ph.D. (1957) degrees from the University of Buenos Aires, Argentina. After being an Associate Neurologist at the St. Mary’s Group of Hospitals in St. Louis, Eduardo was a fellow neuroscientist in the McLean Hospital at Harvard University, where he worked in the laboratory of Professor Jordi Folch-Pi. Eduardo pioneered research on encephalitogenic proteins and was particularly interested in the role of lipids and proteolipids in myelin membrane stability and in multiple sclerosis. In 1963, he returned to Buenos Aires where he assembled his own research group and began a lifetime commitment as an educator and researcher. He rose through the ranks becoming a full Professor in the Department of Biological Chemistry at the School of Pharmacy and Biochemistry in the University of Buenos Aires, where he was honoured with the title of Emeritus Professor in 2005. He authored numerous publications, chaired a myriad of both national and international symposia and served in several scientific societies. Together with his wife, Dr. Juana Maria Pasquini, he formed one of the most prolific South American training groups in neuroscience. He mentored countless young Argentine scientists, humbly and unwittingly influencing the minds of many colleagues around the globe. We will forever miss Eduardo, not only for his sharp intelligence but also for his keen smile, extraordinary kindness, unique sense of humour and wholehearted love for the advancement of the young.
Robert Katzman, M.D., Professor Emeritus of Neurosciences, former chair of the Department of Neurosciences and founding director of the Shirley-Marcos Alzheimer’s Disease Research Center (ADRC) at the University of California, San Diego School of Medicine died Tuesday, September 16, at his home after a long illness. He was 82 years old.
"My only concern when Saul died was the relief that came with Bob's appointment and the feeling that ourfuture as a department was in good hands. Bob was always appreciative of our work and a firm supporter when support was needed" commented Bob Ledeen who was at Einstein during Katzman's tenure there.
An internationally known leader in Alzheimer’s research, Katzman was instrumental in establishing the ADRC at UC San Diego in 1984, one of the original five Alzheimer’s Disease Research Centers of its kind in the country funded by the National Institute on Aging. He held the Florence Riford Chair for Research in Alzheimer’s Disease at UC San Diego from 1984 until his retirement in 1995. Katzman was also a founder of the national Alzheimer’s Association, an achievement he once remarked was the one of which he was most proud. His landmark 1976 editorial in the American Medical Association’s “Archives of Neurology” was the first to state the prevalence and severity of Alzheimer’s disease, calling it a “major killer.” He was a strong advocate for increased funding for research in the disease and, in part due to Katzman’s influence, federal funding in Alzheimer’s research grew from $5 million in 1980 to over $300 million by 1996.
Dr. Katzman was an undergraduate at the U. of Chicago and attended Harvard Medical School, graduating cum laude in 1953. Katzman’s academic career developed at the Albert Einstein College of Medicine in the Bronx, New York. He was chair of neurology there from 1964 until 1984, when he moved to UC San Diego. He received the 1960 S. Weir Mitchell Award from the American Academy of Neurology, and was a co-editor of the first neurochemistry text Basic Neurochemistry (1972), a book now in its seventh edition. His work on brain electrolytes was summarized in a book written with Dr. Hanna Pappius and published in 1972 entitled Brain Electrolytes and Fluid Metabolism.
A full biography of Robert Katzman can be found at: Dr. Robert Katzman
Dr. Steven E. Pfeiffer, 67, died on Sunday, August 26, 2007 after a two year struggle with bladder cancer. Dr. Pfeiffer graduated from Carleton College in Northfield, MN and received his doctorate in molecular biology from Washington University in St. Louis, MO. He was a postdoctoral fellow with Dr. Gordon Sato at Brandeis University in Waltham, MA. For the past 38 years Steve worked as a professor of microbiology and neuroscience at the U Conn Health Center in Farmington, CT. Dr. Pfeiffer was world-reknowned for his knowledge of epigenetic regulators and stages of oligodendrocyte development. Steve was a founding member of and clarinetist for the Farmington Valley Symphony Orchestra and an avid traveler. He and his wife Carol shared their love of camping with their three daughters and their beagles. He created beautiful outdoor spaces, including the woods and path around his home and a Zen garden. Steve was a mentor to countless students and colleagues and a very active member of the Society for Neurochemistry. His keen intelligence, boundless curiosity, sense of humor, optimism and compassion will be deeply missed.
For a more complete tribute to Dr. Pfeiffer go to: Pfeiffer
Dr. Lloyd A. Horrocks, age 75, died unexpectedly at The Ohio State University Hospital on Saturday morning, August 18, 2007. Professor Horrocks earned his Ph.D. in physiological chemistry from The Ohio State University and worked as a Research Associate at the Cleveland Psychiatric Institute from 1960-1968 before rejoining the Department of Physiological Chemistry (now Molecular and Cellular Biochemistry) at The Ohio State University as an Assistant Professor in 1968. He was promoted to full Professor in 1973 and served in that capacity until he retired in 1992. Lloyd is best known for his research on brain phospholipid metabolism, especially plasmalogen metabolism, and on phospholipases A2 in the brain. He authored over 350 research publications, edited 7 books, and wrote 2 monographs during his career. He was the Editor-in-Chief of Neurochemical Pathology (now J. Molecular Neuroscience). He served ASN as a member of Council and on numerous ASN committees. He served on numerous editorial advisory boards (J. Neurochemistry, J. Lipid Research, Lipids, and Neurochemical Research), on grant review panels, and mentored many graduate students and post-doctoral colleagues. Dr. Horrocks was truly a gentleman who was liked and will be missed by his friends, students and colleagues.
For a more complete tribute to Dr. Horrocks go to: Horrocks
Robert E. Jewart was born April 12, 1925, on Easter Sunday in Port Allegheny, PA. He had a passion for flying and joined the Air Corp in 1945. Just after the war, it was a great time for pilots with the startup of many small airlines. In 1951 he joined Eastern Airlines, and within one year became a Captain and then after 33 years of service retired from Eastern Airlines at Seniority #12. I am certain that many of you flew with Captain Jewart in your travels over the years. He was a man of few words yet communicated in a way that was understood and respected by every person he touched. Hunting, fishing, pruning…any activity outdoors is where you would find him. A man that was always willing to help in a way that taught you to grow and prosper for yourself. Life lessons…never a handout. He will be missed by family and friends. We wish him God’s speed on his last flight home.
ASN Members: I would like to thank all of you for your kind words, cards and support for the loss of my father. He was a giant in my eyes and I expected him to live forever. Your thoughts and prayers filled my heart and proved, once again, that ASN is indeed a wonderful family.
Dr. Bernard Haber passed away on July 23, 2007, after a long battle with diabetes. Bernard was a member of the faculty of UTMB from 1971 until his retirement in 1999. Bernard was Editor in Chief of the Journal of Neuroscience Research and served as liaison between the American and International Societies for Neurochemistry until his health no longer allowed it. In 2005 the ASN created the Bernard Haber Award to recognize his outstanding contributions to the development and strengthening of relationships between the ASN and other neuroscience societies. He was semi-famous for his gourmet cooking and infamous for his wild and crazy parties. Bernard celebrated life and was unforgettable to those who had met him. Contributions to the Bernard Haber Award Fund may be made in his memory.
For a more complete tribute to Dr. Haber go to: Haber