SATURDAY, MARCH 18
|
12:00 pm - 6:00 pm |
ASN Registration Desk Open |
Salon B/C Foyer
|
12:00 pm - 5:00 pm |
ASN Council Meeting I |
Arkansas Ballroom |
3:00 pm - 3:30 pm |
Coffee Break |
Salon B/C Foyer
|
4:00 pm - 5:30 pm
|
ASN Public Policy Forum: Alzheimer's and You
        
Chairs: Sue Griffin, PhD - University of Arkansas for Medical Sciences
& Steve Barger, PhD - University of Arkansas for Medical Sciences
This Forum will focus on the patient – disease progression and brain changes accompanying cognitive decline; on the caregivers - stress, fatigue, and out-of-pocket costs; and on research – treatment and prevention successes and failures.
- Introduction to Alzheimer’s Disease, with Broad Stroke Assessment of Brain Changes and the Impact of Dementia in a Small Southern State - Arkansas - Sue Griffin, PhD, University of Arkansas for Medical Sciences
- National Impact of Alzheimer’s and its Care - Susan Neyman, Alzheimer’s Association, Arkansas
- The Importance of Community Actions and Statewide and Local Outreach to Patients, Caregivers, and Activists - Elise Siegler, Alzheimer’s Arkansas and Claudia Beverly, PhD, RN, FAAN, Hartford Center of Geriatric Nursing Excellence and The Arkansas Aging Initiative at the University of Arkansas for Medical Sciences
-
Where We Are in Scientific Advances Toward Treatment and Prevention of Alzheimers - Steve Barger, PhD, University of Arkansas
|

Conway
|
6:00 pm - 7:30 pm
|
ASN President's Welcome Reception Hosted by Sponsored by
|
Salon A
|
SUNDAY, MARCH 19
|
7:00 am - 6:00 pm
|
ASN Registration Desk Open
|
Salon B/C Foyer
|
8:15 am - 8:30 am
|
President’s Welcome & Introductions New Member Recognition / YIEE Award Recognition
|
Salon A
|
8:30 am - 9:30 am
|
Presidential Lecture 01: Circuit Assembly and Reassembly in the Retina
 Rachel Wong, PhD - University of Washington Chair: Doug Feinstein
|
Salon A
|
9:30 am - 10:00 am
|
Coffee Break: View Posters & Visit Exhibits
|
Salon B/C & Foyer
|
10:00 am - 12:00 pm
|
Plenary Lecture PL01: Glial-Glial Interactions in Development & Disease Jordi Folch-Pi Memorial Lecture
      
Chair: Sarah Kucenas, University of Virginia
- Adenosine signaling mediates glial segregation at the motor exit point transition zone - Sarah Kucenas, University of Virginia
- How do astrocytes develop a complex morphology and attain their synaptogenic function? - Jeff Stogsdill, Duke University Medical Center
- Homeostatic Interactions Among Oligodendrocyte Precursor Cells (OPCs) in Health and Diseases - Hui Zong, University of Virginia
- The Glide/Gcm fate determinant controls initiation of collective cell migration by regulating Frazzled - Angela Giangrande, France Université de Strasbourg
|
Salon A
|
12:15 pm - 1:30 pm
|
Lunch with Presidential Speaker: Rachel Wong, PhD Ticket Required ($15) - Limited to 20 Student/Post Docs
|
Hoffman
|
1:30 pm - 3:30 pm
Sponsored by

|
S01 - Proteolipid Protein: Are You Better With It or Without It?
      
Chair: Robert Skoff, Wayne State University
- Myelin devoid of proteolipid protein impacts brain function in young adult mice - Wendy Macklin, University of Colorado
- What makes PLP1 gene expression tick? - Patricia Wight, University of Arkansas
- Prospect for stem cell approaches in the treatment of demyelinating leukodystropies - Anne Baron-Van Evercooren, Pierre and Marie Curie University
- The absence of proteolipid protein isneuroprotective in neonatal hypoxic ischemic mice - Robert Skoff, Wayne State University
|
Salon A
|
1:30 pm - 3:30 pm
Sponsored by

|
S02 - Lipid Metabolism in Neural Stem Cells, Brain Development & Function
      
Chair: Guanghu Wang, Medical College of Georgia at Augusta University
- Lipid Metabolism in Adult Neural Stem Cell Biology and Alzheimer's Disease - Karl Fernandes, Université de Montréal
- The blood brain barrier and fatty acid uptake: Role of the BBB as a metabolic barrier? - Eric Murphy, University of North Dakota
- Deoxysphingolipids as taxanes neurotoxic mediators in the peripheral nervous system - Stefanka Spassieva, Texas A&M Health Sciences Center
- Ceramide Regulates Cilia Formation in Human Neural Progenitor Cells and Murine Ependymal Cells - Guanghu Wang, Medical College of Georgia at Augusta University
|
Conway
|
3:30 pm - 4:00 pm
|
Coffee Break: View Posters & Visit Exhibits
|
Salon B/C & Foyer
|
4:00 pm - 5:30 pm |
C01 - Traumatic Brain Injury Affects Neurovascular Unit Function
     
Chair: Stefanie Robel, Virginia Tech Carilion Research Institute
- Blast-related mild traumatic brain injury: The consequences of more than a decade at war - David Cook, University of Washington
- Damaged astrocytes affect neurovascular unit function after repeated mild traumatic brain injury/concussion - Stefanie Robel, Virginia Tech
- Interogation of collateral vessel remodeling following traumatic brain injury - Michelle Theus, Virginia Tech
|
Salon A
|
4:00 pm - 5:30 pm |
C02 - Chewing the Fat about Chewing the Fat: Interactions of Diet and Digestion with Cognition
     
Chair: Steve Barger, Univ. Arkansas for Medical Sciences
- Amyloid Precursor Protein Impacts on Peripheral Metabolism: Potential for Indirect Effects on CNS - Steve Barger, Univ. Arkansas for Medical Sciences
- Characterizing Alzheimer's Disease in the Enteric Nervous System - Colin Combs, University of North Dakota
- Surprising Sources of CNS Inflammation - Annadora Bruce-Keller, Louisiana State University
|
Conway
|
4:00 pm - 5:30 pm
|
OR01 - Oral Session I: Presentation of Selected Abstracts
- Sox17 Regulates Sox2 and Tcf7L2/Tcf4 Induction, and Promotes Oligodendrocyte Progenitor Response to Demyelination - Li-Jin Chew
- Protofibrillar Amyloid-Beta is Preferentially Internalized by Primary Microglia - Lisa Gouwens
- Optical Interrogation of the Supramolecular Organization of Gap Junctions- How Nexus Structure Regulates Cellular Function of Glia - Randy Stout
- Acute Neuroinflammation Induces Axon Initial Segment Structural Plasticity - Savannah Benusa
- Absence of Mtorc2 Signaling in Oligodendrocyte Precursor Cells Hinders Differentiation and Myelination - Hannah Hathaway
- Nectin-Like 2 (Necl-2) Cell Adhesion Molecule is a Negative Regulator of Schwann Cell Myelination - Ming-Shuo Chen
|
Harris Brake
|
5:30 pm - 7:00 pm
|
Poster Session I - Authors Present Wine & Cheese Served
|
Salon B/C & Foyer
|
7:30 pm - 10:00 pm |
Student / Post Doc Mingle Ticket Required - Limited to Students / Post Docs only
|
Pröst Restaurant |
MONDAY, MARCH 20
|
7:00 am - 5:00 pm
|
ASN Registration Desk Open
|
Salon B/C Foyer
|
8:15 am - 8:30 am |
General Session - Opening Remarks Jordi Folch-Pi Award - Presented by Eric Murphy
|
Salon A
|
8:30 am - 9:30 am |
Presidential Lecture 02: Promoting Axon Regeneration by Manipulating Intrinsic Growth Capacity of Adult CNS Neurons
  Zhigang He, PhD - Harvard University
|
Salon A
|
9:30 am - 10:00 am
|
Coffee Break: View Posters & Visit Exhibits
|
Salon B/C & Foyer
|
10:00 am - 12:00 pm
|
Plenary Lecture PL02: ER Stress and Neurodegeneration
       
Chairs: Yang Hu, Stanford University & Jonathan Lin, University of California San Diego
- The Role of ER Protein Misfolding in Neurodegeneration: Potential Therapeutic Approaches - Randal Kaufman, Sanford Burnham Prebys Medical Discovery Institute
- Mutations in ER Stress Regulator, ATF6, Cause the Photoreceptor Disease Achromatopsia - Jonathan Lin, University of California San Diego
- The Integrated Stress Response Provides Oligodendrocyte Protection Against CNS Inflammation - Brian Popko, University of Chicago
- Translational Regulatory Mechanisms in Pathological Learning - Mauro Costa-Mattioli, Baylor College of Medicine
|
Salon A
|
12:15 pm - 1:30 pm |
Women in Neurochemistry Lunch  Ticket Required ($25 Faculty / $15 Student)
|
Arkansas Ballroom
|
12:15 pm - 1:30 pm
|
Lunch with Presidential Speaker: Zhigang He, PhD Ticket Required ($15) - Limited to 20 Student/Post Docs
|
Hoffman
|
1:30 pm - 3:30 pm |
S03 - Defining Neuropsychiatric Disorders by Using Human Induced Pluripotent Stem Cell (iPSC) Technologies
      
Chairs: Emanuel DiCicco-Bloom, Rutgers University & James H. Millonig, Rutgers University
- Pluripotent stem cells as model for understanding and treating Fragile X Syndrome - Xinyu Zhao, University of Wisconsin-Madison
- Generating idiopathic autism iPSCs to characterize individual-specific mechanisms of disease - James H. Millonig, Rutgers University
- Abnormalities in proliferation, differentiation and cell migration cluster in idiopathic autism - Emanuel DiCicco-Bloom, Rutgers University
- Developing 3D human brain models to study development and disease - Sergiu Pasca, Stanford University
|
Salon A
|
1:30 pm - 3:30 pm |
S04 - ApoE as an AD Therapeutic Target: Novel Approaches
       
Chairs: Mary Jo LaDu, University of Illinois at Chicago & Leon Tai, University of Illinois at Chicago
- ApoE4-containing lipoproteins in the CNS: "Repurposing" drugs from the cardiovascular field - Mary Jo LaDu, University of Illinois at Chicago
- APOE4 modulated cerebrovascular dysfunction as a potential therapeutic target for Alzheimer's disease - Leon Tai, University of Illinois at Chicago
- Mimetics of apolipoprotein-E as a novel therapeutics for Alzheimer's Disease and Cancer - Michael P. Vitek, Duke University
- Anti-inflammatory rescue of APOE4-related phenotypes - G. William Rebeck, Georgetown University
|
Conway
|
3:30 pm - 4:00 pm |
Coffee Break: View Posters & Visit Exhibits
|
Salon B/C & Foyer
|
4:00 pm - 5:30 pm |
C03 - Major Advancements in Your PhD Career
       
Chairs: Haley Titus, Northwestern University & Joshua Burda, UCLA
- Young Investigators Funding Opportunities Session - Sanoj Suneja, National Institute on Aging/NIH/DHHS
- How to Find a Good Postdoctoral Position Fit - Joshua Burda, UCLA & Haley Titus, Northwestern University
- Applying for a Job in Academia - Monica Carson, University of California, Riverside
- Successful Transitioning from Academia to Industry - Karen Chandross, Sanofi
- Write Well and Review Constructively - Scott Brady, University of Illinois, Chicago
|
Salon A
|
4:00 pm - 5:30 pm
|
C04 - Glial-Neuronal Interactions in Epileptogenesis
      
Chairs: Thimmasettappa Thippeswamy, Iowa State University & Devin Binder, University of California, Riverside
- The Role of Astroglial Glutamine Synthetase in Health and Disease - Tore Eid, Yale University
- Targeting immune and vascular signaling after brain injury to limit epileptogenesis - Vijaylakshmi Santhakumar, Rutgers University
- Role of astrocyte channels and transporters in epileptogenesis - Devin Binder, University of California, Riverside
- Neuroinflammation mediators as targets for disease modification in epilepsy - Thimmasettappa Thippeswamy, Iowa State University
|
Conway
|
4:00 pm - 5:30 pm |
C05 - Neuropathologic Mechanisms, Consequences, and Intervention in Fetal Alcohol Spectrum Disorders
      
Chairs: Sandra Mooney, University of Maryland & Cynthia Kane, University of Arkansas
- Overview of FASD - Antonio Noronha, NIAAA
- Plasma microRNAs during pregnancy predict variations in infant outcomes due to prenatal alcohol expo - Rajesh Miranda, Texas A&M University
- Developmental stage-dependent effects of early gestational ethanol exposure: Neuroimaging - Scott Parnell, University of North Carolina
- Prenatal ethanol exposure alters brain structure and behavior: Can nutritional interventions improve outcomes? - Sandra Mooney, University of Maryland
- Alcohol-induced neuroinflammation in fetal alcohol spectrum disorders and potential intervention - Cynthia Kane, University of Arkansas
|
Harris Brake
|
5:30 pm - 7:30 pm |
ASN Business Meeting
|
Salon A
|
TUESDAY, MARCH 21
|
7:00 am - 5:00 pm |
ASN Registration Desk Open
|
Salon B/C Foyer
|
8:15 am - 8:30 am |
General Session - Opening Remarks Marion Kies Award - Presented by Astrid Cardona and Emma Wilson
|
Salon A
|
8:30 am - 9:30 am
|
Presidential Lecture 03: Immunosuppression Regulates Amino Acid Metabolism in the Brain: Implications for Alzheimer's Disease George Siegel Basic Neurochemistry Textbook Lecture
   Carol Colton, PhD - Duke University Chairs: George Siegel & Scott Brady
|
Salon A
|
9:30 am - 10:00 am
|
Coffee Break: View Posters & Visit Exhibits
|
Salon B/C & Foyer
|
10:00 am - 12:00 pm
Sponsored by

|
Plenary Session PL03: Tubulinopathies and Related Disorders
      
Chair: Judy Liu, George Washington University
- Tubb4a and Myelination in the Mouse - Karel Liem, Yale University
- Regulation of Microtubule Function in Neurons by Acetylation at Novel Sites - Jill Kathleen Wildonger, University of Wisconsin
- TUBB4A mutations are associated with mutation specific cell selective abnormalities - Quasar Padiath, University of Pittsburgh
- Deletion of TUBB3 delays peripheral axon regeneration - Long Cheng, Harvard University
|
Salon A
|
12:15 pm - 1:30 pm |
Lunch with Presidential Speaker: Carol Colton, PhD Ticket Required ($15) - Limited to 20 Student/Post Docs
|
Hoffman
|
12:15 pm - 1:30 pm |
ASN 2018 Planning Committee Meeting
|
Manning
|
1:30 pm - 3:30 pm |
S05 - Regulation of Mitochondrial Metabolism: New Insights & Mechanisms
       
Chairs: Mary McKenna, Univ. of Maryland & Arne Schousboe, Univ. of Copenhagen
- Flexible fueling: Investigating hippocampal primary neuron resiliency to metabolic challenges - Courtney Sobieski, Washington University
- Succinylation by the alpha-ketoglutarate dehydrogenase complex alters enzyme function and varies with metabolic state - Gary Gibson, Cornell University
- Visualization of NAD+ and NADH in human brain - Wei Chen, University of Minnesota
- Exploring the role of NAMPT-mediated NAD+ biosynthesis in mitochondrial function and energy metabolism - Jun Yoshino, Washington University
|
Salon A
|
1:30 pm - 3:30 pm
Sponsored by

|
S06 - Interacting Signaling Pathways at the Crossroads to Demyelinating and Remyelinating Responses
       
Chair: Bridget Shafit-Zagardo, Albert Einstein College of Medicine & Cheryl Dreyfus, Rutgers University
- Inducible Genetic Fate Labeling for In Vivo Detection of Sonic Hedgehog Signaling During Corpus Callosum Myelination in Postnatal Development and Following Chronic Demyelination - Regina Armstrong, Uniformed Services University of the Health Sciences
- Extensive axonal damage and demyelination are observed in Gas6-/-Axl-/- double-knockout (DKO) mice following demyelination - Bridget Shafit-Zagardo, Albert Einstein College of Medicine
- TrkB on oligodendrocytes directly mediates BDNF"s effects on myelin following a demyelinating lesion - Cheryl Dreyfus, Rutgers University
- Loss of TSC1 in Adult OPCs Enhances Axon Remyelination and Increases Myelin Thickness after a Focal Demyelination - Teresa Wood, Rutgers University
|
Conway
|
3:30 pm - 4:00 pm |
Coffee Break: View Posters & Visit Exhibits
|
Salon B/C & Foyer
|
4:00 pm - 5:30 pm |
C06 - Roles of Lipids in Neurological Disorders
       
Chairs: Xianlin Han, Sanford Burnham Prebys Medical Discovery Institute & Xiao-Ming Xu, Indiana University
- Phospholipase A2 as a novel target for neuroprotection after spinal cord injury - Xiao-Ming Xu, Indiana University
- Bis(monoacylglycero) phosphate as a secondary storage lipid in the gangliosidoses - Zeynep Akgöç, Boston College
- Activity of Water Channel Protein in Post-traumatic Syringomyelia Formation - Christopher B. Shields, Norton Neuroscience Institute
- Loss of sulfatide: The key node leading to the pathogenesis of Alzheimer's Disease - Xianlin Han, Sanford Burnham Prebys Medical Discovery Institute
|
Salon A
|
4:00 pm - 5:30 pm
Sponsored by



|
C07 - Cellular and Molecular Mechanisms of Peripheral Myelin Homeostasis During Development and in Diseases
       
Chairs: Haesun Kim, Rutgers University & Corey Heffernan,
- Proteostasis in Normal and Diseased Myelinating Schwann Cells - Lawrence Wrabetz, Buffalo University
- Cholesterol homeostasis in neuropathic Schwann cells - Lucia Notterpek, University of Florida
- Choline and lipid homeostasis in PNS myelination - Corey Heffernan, Rutgers University
- Abnormal Myelin Permeability in PMP22 Deficiency - Jun Li, Vanderbilt University
|
Conway
|
4:00 pm - 5:30 pm |
OR02 - Oral Session II: Presentation of Selected Abstracts
- Partial Rescue of Rett Syndrome Phenotypes via Modulation of Nf-Κb Signaling and Vitamin D Supplementation in Mecp2-Null Mice - Jessica MacDonald
- Lrrtm1 Contributes to the Assembly of Complex Retinogeniculate Synapses in Mouse Visual Thalamus - Aboozar Monavarfeshani
- Mutant Huntingtin Expression Induces Jnk Activation and Promotes Axonal Degeneration in Vulnerable Cortical Neuron
Subpopulations - Nichole Mesnard-Hoaglin
- Examination of the Class IV Semaphorin Sema4A in Multiple Sclerosis Pathogenesis - Brian Chiou
- Klotho Regulates Postnatal Neurogenesis and Protects Against Age-Related Loss of Dentate Gyrus Function - Gwendalyn King
- Morphological and Functional Consequences of Hiv-1 Tat on Area Ca1 of the Hippocampus - William Marks
|
Harris Brake
|
5:30 pm - 7:00 pm |
Poster Session II - Authors Present Wine & Cheese Served
|
Salon B/C & Foyer
|
7:00 pm - 10:00 pm
|
Neurochemical Research Editorial Board Meeting
|
Offsite
|
WEDNESDAY, MARCH 22
|
7:00 am - 5:00 pm |
ASN Registration Desk Open |
Salon B/C Foyer |
8:15 am - 8:30 am |
General Session - Opening Remarks ASN Neuro Award - Presented by Monica Carson Sanofi Award - Presented by Karen Chandross Biolegend Award - Presented Patrick Zou
|
Salon A
|
8:30 am - 9:30 am
|
Presidential Lecture 04: Astrocyte Control of Neural Circuits and Behavior
 Marc Freeman, University of Massachusetts
|
Salon A
|
9:30 am - 10:00 am |
Coffee Break & Visit Exhibits / Remove Posters
|
Salon B/C & Foyer
|
10:00 am - 12:00 pm
Sponsored by
|
Plenary Lecture PL04: Strategies for Promoting CNS Remyelination in Demyelinating Disorders
      
Chair: Jeffrey Huang, Georgetown University
- Regulation of Inflammation Resolution in CNS Remyelination - Jeffrey Huang, Georgetown University
- Oligodendrocyte Precursors migrate along vasculature in the developing nervous system - Stephen Fancy, UCSF
- The Role of Endothelin-1 signaling in oligodendrocyte development and regeneration - Vittorio Gallo, Children's National Medical Center
- Small molecule inducers of remyelination and their associated mechanisms of action - Luke Lairson, The Scripps Research Institute
|
Salon A
|
12:00 pm - 3:30 pm |
ASN Council Meeting II
|
Manning
|
12:15 pm - 1:30 pm |
Lunch with Presidential Speaker: Marc Freeman, PhD Ticket Required ($15) - Limited to 20 Student/Post Docs
|
Hoffman
|
1:30 pm - 3:30 pm
|
S07 - Glial Cells of the Second Brain: Novel Roles of Enteric Glia in Health and Disease Marian Kies Symposium
      
Chair: Vladimir Grubisic, Michigan State University
- Heterogeneity of enteric glia and neuron-glia interactions in the enteric nervous system - Werend Boesmans, University of Leuven, Belgium
- Enteric glia actively regulate gut reflexive behaviors such as peristalsis and epithelial functions - Vladimir Grubisic, Michigan State University
- Vertebrate enteric glial cells: What the Zebrafish can tell us - Sarah McCallum, Francis Crick Institute
- Where the gut meets the brain - Diego V. Bohorquez, Duke University
|
Salon A
|
Sponsored by  |
S08 - Extracellular Vesicles in Neurodegenerative Disease
      
Chair: Michael B. Dinkins, Augusta University
- Improvement of Alzheimer's Disease Pathology by Targeting Neutral Sphingomyelinase-2 - Michael Dinkins, Augusta University
- Microvesicle shedding from microglia and interactions with amyloid-β - Michael Nichols, University of Missouri-St. Louis
- Extracellular vesicles in Multiple Sclerosis - Maria Irene Givogri, University of Illinois-Chicago
- Exosome pathway as a new therapeutic target of tau propagation in Alzheimer's Disease - Tsuneya Ikezu, Boston University
|
Conway
|
3:30 pm - 4:00 pm |
Coffee Break & Visit Exhibits
|
Salon B/C & Foyer
|
4:00 pm - 5:30 pm
|
C08 - Multimodal Approach Targeting Post-Stroke Inflammatory Responses for Therapeutic Intervention
       
Chairs: Surojit Paul, Univ. of New Mexico & Eduardo Candelario-Jalil, Univ. of Florida
- Role of brain-enriched tyrosine phosphatase Ptpn5 in regulating neuroinflammation in ischemic stroke - Surojit Paul, University of New Mexico
- Activation of the liopxinA4 pathway promotes resolution of neuroinflammation after ischemic stroke - Eduardo Candelario-Jalil, University of Florida
- TREM2 promotes phagocytosis and improved recovery following experimental brain ischemia and trauma - Midori A Yenari, University of California, San Francisco
- Comorbidity-modified neuroinflammation in ischemic stroke: role of CD36 - Sunghee Cho, Weill Cornell Medicine at Burke Medical Research Institute
|
Salon A
|
|
C09 - Principles of Neurogliopathology
      
Chairs: Nina Vardjan, University of Ljubljana
- Glial calcium signalling in neurodegenerative diseases - Vladimir Parpura, University of Alabama Birmingham
- Live imaging of brain injury depolarizations and their impact on neuroglia - Sergei A. Kirov, Medical College of Georgia
- Astrocytic calcium- and cAMP-mediated functions in health and diseases - Nina Vardjan, University of Ljubljana
- Autotaxin: a regulator of oligodendrocyte differentiation and CNS myelination - Babette Fuss, Virginia Commonwealth University
|
Conway
|
|
C10 - Organ-on-a-Chip Technology: Recent Advances & Challenges
       
Chair: Syed F. Ali, National Center for Toxicological Research & Hector Rosas-Hernandez, National Center for Toxicological Research
- Human Microphysiological Systems: Tissues-on-Chips for In Vitro Safety, Toxicity and Efficacy Testing - Lucie Low, National Center for Advancing Translational Sciences, NIH
- High-speed and biaxial stretch as in vitro models of traumatic brain injury to the blood-brain barrier - Hector Rosas-Hernandez, National Center for Toxicological Research
- Cardiac and neurovascular systems on-a-chip - Kartik Balachandran, University of Arkansas
- Vascularization of Organ on a Chip Systems - Kapil Pant, CFD Research Corporation SynoVivo, Inc.
|
Harris Brake
|
7:30 pm - 10:30 pm
|
ASN Closing Reception / Dinner / Dancing Hosted by   All registered delegates are invited to attend the closing reception.
|
Clinton Presidential Library
|