ASN * American Society for Neurochemistry
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 Saturday, 3/24
 Sunday, 3/25
Monday, 3/26
Tuesday, 3/27
Wednesday, 3/28

 = Meeting      food dining icon= Ticketed Event with Lunch     ticket icon=Ticketed Event

SATURDAY, MARCH 24

12:00 pm - 6:00 pm
yin  and  yang ASN Registration Desk Open 

Concourse 201

12:00 pm - 5:00 pm  ASN Council Meeting I Room 8
3:00 pm - 3:30 pm
Coffee Break

Room 1/2/3 Foyer

4:00 pm - 5:30 pm

ASN Public Forum: Concussions and traumatic brain injuries 
in children and adults
Room 1/2/3
6:00 pm - 7:30 pm

ASN President's Welcome Reception                        
Hosted by ASN logo  

Concourse 201

SUNDAY, MARCH 25

7:00 am - 6:00 pm

yin  and  yang ASN Registration Desk Open

Concourse 201

8:15 am - 8:30 am

President’s Welcome & Introductions
New Member Recognition / YIEE Award Recognition

Raincross Ballroom  

8:30 am - 9:30 am

Presidential Lecture 01: Integrative Genomics in Neuropsychiatric Disorders

Basic Neurochem Lecture

GeschwindDaniel

Daniel Geschwind, MD, PhD - University of California Los Angeles

Raincross Ballroom  

9:30 am - 10:00 am

Coffee Break: View Posters & Visit Exhibits  

Exhibit Hall C/D

10:00 am - 12:00 pm

Plenary Lecture PL01:  Mechanisms and Consequences of Immune Activation in Neuropsychiatric Disorders

Chair: Harley Kornblum, Professor, UCLA School of Medicine
Co-Chair: Alcino Silva, Professor, UCLA School of Medicine

  1. Novel roles for immune molecules in the brain during development and disease - A. Kimberley McAllister, PhD, Professor, University of California, Davis
  2. Mechanisms of social memory deficits in mice and men revealed by postnatal immune activation - Alcino Silva, PhD; Professor, UCLA School of Medicine
  3. Altered functional connectivity and adult correction in a maternal inflammation-induced model of autism - Harley Kornblum, MD, PhD; Professor, UCLA School of Medicine
  4. The human side of inflammation and autoimmunity in ASD - Karen Jones, PhD; Postdoctoral Scholar, University of California, Davis

Raincross Ballroom

12:15 pm - 1:30 pm

food dining icon  Young Investigator Workshop I - Finding the Right Fit:  Academia

Room 7

1:30 pm - 3:30 pm

S01: From Single Cells to Assembled 3D Brain Cultures: New Tools in Neuroscience

Folch-Pi Symposium

Chair: Sergiu Pasca, MD, Assistant Professor, Stanford University School of Medicine

  1. TBA - Sergiu Pasca, MD; Assistant Professor, Stanford University School of Medicine
  2. TBA - Bianxiao Cui, PhD; Assoc. Professor, Stanford University
  3. Identification of an astrocyte-secreted factor that induces synapse maturation through recruitment of GLUA2 ampars to synapses - Elena Blanco-Suarez, PhD; Salk Institute for Biological Studies
  4. TBA - Matt Thomson; CalTech

Raincross A/D

1:30 pm - 3:30 pm

S02: RNA Processing and Regulation in Brain Development and Disorders

Chair: Sika Zheng, PhD, Assistant Professor, University of California Riverside School of Medicine
Co-Chair: Gene Yeo, PhD; Professor, University of California, San Diego

  1. The Role of the NMD Factor UPF3B in Intellectual Disability as Defined in a Mouse Model and Human iP - Miles Wilkinson, PhD; Professor, University of California, San Diego
  2. Assigning the molecular functions of hundreds of RNA binding proteins at scale - Gene Yeo, PhD; Professor, University of California, San Diego
  3. Dynamic post-transcriptional regulation of neural stem cells in the developing neocortex - Debra Silver, PhD; Assoc. Professor, Duke University
  4. RNA regulatory networks in neurodevelopment - Chaolin Zhang, PhD; Assist. Professor, Columbia University

Raincross B/E 

3:30 pm - 4:00 pm

Coffee Break: View Posters & Visit Exhibits

Exhibit Hall C/D

4:00 pm - 5:30 pm

C01: Glia in Model Organisms

Chair: Margaret Ho, PhD, Assoc Prof, School of Life and Technology, Shanghai Tech University, Shanghai, China
Co-Chair: Vladimir Parpura, MD, PhD, Professor, University of Alabama at Birmingham

  1. The role of astroglia in the enteric nervous system and gut function - Vladimir Parpura, MD, PhD; Professor, University of Alabama at Birmingham
  2. Zebrafish genetics uncovers new regulators of myelination - Kelly Monk, PhD; Professor, Vollum Institute/Oregon Health and Sciences University
  3. Glia-neuron interaction in Drosophila mushroom body development - Margaret Ho, PhD; Associate Professor, Shangai Tech University, China
  4. Molecular mechanisms governing glial control of animal behavior - Shai Shaham, PhD; Professor, Rockefeller University

Raincross A/D

4:00 pm - 5:30 pm

C02:  Neurosteroids: New Insights into their Synthesis and Neuroprotective Mechanisms

Chair: Michael Schumacher, PhD, Professor, University of Paris-Sud, France
Co-Chair: Jason Paris, PhD, Assistant Professor, University of Mississippi

  1. Cholesterol transport mechanisms in steroid and neurosteroid biosynthesis - Vassilios Papadopoulos, D. Pharm., PhD; Professor, University of Southern California
  2. A role of endogenous brain progesterone and receptors in stroke neuroprotection - Michael Schumacher, PhD; Professor, University of Paris-Sud, France
  3. Activation of extrasynaptic GABA-A receptors by neurosteroids and its role in CNS disorders - Samba Reddy, PhD; Professor, Texas A&M University Health Science Center
  4. Allopregnanolone attenuates neurotoxicity associated with the HIV-1 regulatory protein Tat - Jason Paris, PhD; Assistant Professor, University of Mississippi

Raincross B/E

4:00 pm - 5:30 pm

OR01 - Oral Session I: Presentation of Selected Abstracts

Raincross C/F

5:30 pm - 7:00 pm

Poster Session I - Authors Present                                   
Wine & Cheese Served

Exhibit Hall C/D

7:30 pm - 10:00 pm
food dining icon Student / Post Doc Mingle   
       Ticket Required - Limited to Students / Post Docs only
TBA

MONDAY, MARCH 26

7:00 am - 5:00 pm

yin  and  yang ASN Registration Desk Open

Concourse 201

8:15 am - 8:30 am

General Session - Opening Remarks                                     

Jordi Folch-Pi Award

Raincross Ballroom 

8:30 am - 9:30 am

Presidential Lecture 02: Perinatal Brain Injury: A Story of Altered Trajectory in Brain Development

GalloVittorio

Vittorio Gallo, PhD - Children's National Health System

Raincross Ballroom 

9:30 am - 10:00 am

Coffee Break: View Posters & Visit Exhibits      

Exhibit Hall C/D

10:00 am - 12:00 pm

Plenary Lecture PL02: Understanding the Connection Between Diabetes and Dementia

Chair: Fernanda G. De Felice, Associate Professor, Institute of Medical Biochemistry, Federal University of Rio de Janeiro, Brazil

  1. Central insulin resistance: towards integral model of hypothalamic and hippocampal effects of insulin - Lawrence P. Reagan, PhD; Professor, University of South Carolina School of Medicine
  2. Mental health and allostatic load: 3Ds of insulin resistance - Natalie Rasgon, MD, PhD; Professor, Stanford Center for Neuroscience in Women's Health, Stanford School of Medicine
  3. Molecular connections between Alzheimer's disease and type 2 Diabetes - Fernanda G. De Felice, PhD; Associate Professor, Institute of Medical Biochemistry, Federal University of Rio de Janeiro, Brazil
  4. TBA - Douglas P. Munoz, PhD; Professor, Centre for Neuroscience Studies, Queen's University, Canada

Raincross Ballroom 

12:15 pm - 1:30 pm
food dining icon  Women in Neurochemistry Lunch                                         
        2-DSC 9870
        Ticket Required ($25 Faculty / $15 Student)

Room 1/2/3

1:30 pm - 3:30 pm

S03: Molecular Targets for Axonal Repair and Regeneration

Chair: Jason Hinman, MD, PhD; Assist. Prof., UCLA School of Medicine
Co-Chair: Jack Wang, MD, PhD; Postdoctoral Scholar, UCLA School of Medicine

  1. What are the Molecular Mechanisms of Axonal Degeneration in Stroke? - Jack Wang, PhD; Postdoctoral Scholar, University of California Los Angeles
  2. Evolutionarily conserved mechanisms of axonal damage signaling by DLK/WND kinase - Laura Smithson, PhD; University of Michigan
  3. TBA - Dana McTigue, PhD; Professor, Ohio State University College of Medicine
  4. Mary Logan, PhD; Assist. Professor, Oregon Health & Science University

Raincross A/D 

1:30 pm - 3:30 pm

S04: Molecular Mechanisms of Circuit Assembly and Refinement

Chair: Martin Riccomagno, PhD, Assist. Professor, University of California, Riverside
Co-Chair: Kevin M. Wright, PhD, Assist. Professor, Vollum Institute, Oregon Health & Science University

  1. Dystroglycan is a multifunctional scaffold for neural circuit development - Kevin M. Wright, PhD; Assist. Professor, Vollum Institute, Oregon Health & Science University
  2. Roles of endothelins in establishment of peripheral neural circuitry - Takako Makita, PhD; Assist. Professor, Children's Hospital Los Angeles
  3. Cas signaling adaptor proteins are essential for cortical circuit formation - Martin Riccomagno, PhD; Assist. Professor, University of California, Riverside
  4. Rapid high-resolution phenotyping of sensory nervous system development - Christopher Deppmann, PhD; Assoc. Professor, University of Virginia

Raincross B/E

3:30 pm - 4:00 pm
Coffee Break: View Posters & Visit Exhibits    

Exhibit Hall C/D  

4:00 pm - 5:30 pm

C03: The Extracellular Environment Dictates the Fate of Astrocytes

Marion Kies Coloquium

Chair: Zila Martinez-Lozada, PhD; Postdoctoral Scholar, The Children's Hospital of Philadelphia and University of Pennsylvania

  1. Controlling Astrocyte Diversity in the Mature Brain Through Neuron-Derived Cues - Keith K. Murai, PhD; Professor, Faculty of Medicine, McGill University, Canada
  2. Endothelial Cells Regulate Different Aspects of the Astrocyte Biology - Zila Martinez-Lozada, PhD; Postdoctoral Scholar, The Children's Hospital of Philadelphia & University of Pennsylvania
  3. Fgf8a Regulates Muller Glial Cell Reprogramming and Retina Regeneration in Zebrafish - Daniel Goldman, PhD; Professor of Biological Chemistry, University of Michigan
  4. Normal Aging Induces Astrocyte Reactivity - Laura E. Clarke, PhD; Postdoctoral Scholar, Department of Neurobiology, Stanford University

Raincross A/D

4:00 pm - 5:30 pm

C04: Extracellular Proteolysis that Links Brain and Mind

Chair: Alexander C. Smith, PhD; Assist Professor, Icahn School of Medicine 
Co-Chair: Leszek Kazmarek, PhD; Nenski Institute, Warsaw, Poland

  1. Targeting MMP-9 and perineuronal nets to understand the mechanisms of sensory hyperexcitability in Fragile X Syndrome - Iryna Ethell, PhD; Professor, School of Medicine, University of California, Riverside
  2. Synaptic matrix Metalloproienase-9 links brain and mind - Leszek Kaczmarek, PhD; Professor, Nenski Institute, Warsaw, Poland
  3. MMP-9 in cortical plasticity: Role of microglia - Ania Majewska, PhD; Professor, University of Rochester Medical Center
  4. MMP-9 in cocaine addiction - Alexander Smith, PhD; Assist. Professor, Icahn School of Medicine at Mt. Sinai

Raincross B/E

4:00 pm - 5:30 pm

C05: Modulation of Neurodegeneration by Sex

Chair: Mary Jo LaDu, PhD; Professor, University of Illinois, Chicago

  1. Enhanced effects of APOE4-modulated neurodegeneration in female EFAD transgenic mice - Mary Jo LaDu, PhD; Professor, University of Illinois Chicago
  2. Molecular mechanisms underlying estrogenic regulation of memory formation in female and male mice - Karyn M. Frick, PhD; Professor, University of Wisconsin, Milwaukee
  3. Sex and APOE genotype modulate the relationship between obesity and pathology in Alzheimer’s mice - Christian Pike, PhD; Professor, University of Southern California
  4. Sex differences in ApoE influences on brain microbleeds and responses to air pollution - Caleb Finch, PhD; Professor, University of Southern California

Raincross C/F

4:00 pm - 5:30 pm
YIAC: Young Investigator Workshop on Finding the Right Fit - 
Academia or Industry?

Room 1/2/3

5:30 pm - 7:30 pm

yin  and  yang ASN Business Meeting

Raincross A/D

TUESDAY, MARCH 27

7:00 am - 5:00 pm
ASN Registration Desk Open

Concourse 201 

8:15 am - 8:30 am

General Session - Opening Remarks

Marion Kies Award 

Raincross Ballroom  

8:30 am - 9:30 am

Presidential Lecture 03: Wiring Up the Nervous System - Molecular Mechanisms Underlying Neural Connectivity

KolodkinAlex

Alex Kolodkin, PhD - Johns Hopkins University

Raincross Ballroom  

9:30 am - 10:00 am

Coffee Break: View Posters & Visit Exhibits    

Exhibit Hall C/D 

10:00 am - 12:00 pm

Plenary Session PL03: Roles of Adhesion G-Protein Coupled Receptors in Neurobiology

Chair: Garret Anderson, PhD, Assistant Professor, University of California, Riverside

  1. Metabotropic Mechanosensing Through Adhesion GPCRs - Tobias Langenhan, MD, D. Phil.; Professor, University of Leipzig, Germany
  2. GPR56 mediates tripartite signaling during CNS myelin formation and repair - Xianhua Piao, MD, PhD; Assoc. Professor, Harvard University Medical School
  3. Structural and Functional Basis for Adhesion GPCR Activation - Demet Arac, PhD; Assist. Professor, University of Chicago
  4. Role of Latrophilin Adhesion GPCRs in Synaptic Assembly - Garret Anderson, PhD; Assist. Professor, University of California, Riverside

Raincross Ballroom

12:15 pm - 1:30 pm
food dining icon Young Investigator Workshop II - Finding the Right Fit: Industry

Room 7

12:15 pm - 1:30 pm

ASN 2019 Planning Committee Meeting

Room 8

1:30 pm - 3:30 pm

S05: Activity-Dependent Glial Plasticity: A Quest to Understand the Basics

Chair: Dmitri Rusakov, PhD; Professor, Institute of Neurology, University College London, UK
Co-Chair: Stephane Oliet, PhD; Professor, Neurocentre Magendie, Bordeaux, France

  1. Super-resolution imaging of glial dynamics - Valentin Nägerl, PhD; Professor, Université de Bordeaux, France
  2. Spreading depolarization is the main mechanism of the cortical cytotoxic edema during stroke - Sergei Kirov, Medical College of Georgia
  3. Rapid astrocyte morphology changes support epileptic activity - Christian Henneberger, PhD; Assist. Professor, University of Bonn Medical School, Germany
  4. Contribution of astroglial IP3Rs to Ca2+ signalling and hippocampal plasticity - Stephane Oliet, PhD; Professor, Neurocentre Magendie, Bordeaux, France

Raincross A/D

1:30 pm - 3:30 pm

S06: Astrocytes: From Friends to Foe in Disease                             

Chair: Akshata Almad, PhD; Research Associate, Children's Hospital of Philadelphia

  1. Layer specific Astrocytes regulate dendritic spine density and branching  in normal and disease CNS - Jeffrey Rothstein, MD, PhD; Professor, Johns Hopkins University
  2. Neurotoxic reactive astrocytes are induced by activated microglia - Shane Liddelow, PhD; Assistant Professor, Neuroscience Institute at NYU Langone
  3. Astrocytic contributions in synaptic and behavioral abnormalities of Fragile X Syndrome - Yi Zuo, PhD; Professor, University of California, Santa Cruz
  4. Astrocyte scars do not prevent CNS axon regeneration - Michael Sofroniew, MD, PhD; Professor, University of California, Los Angeles

Raincross B/E

3:30 pm - 4:00 pm
Coffee Break: View Posters & Visit Exhibits 

Exhibit Hall C/D

4:00 pm - 5:30 pm

Sponsored by

NSA logo

WPFlogo

 

C06: Lysosomal-Inflammatory Axis Function in Neurological Health and Disease

Chair: Thomas Kukar, PhD., Assist. Professor, Emory University
Co-Chair: Malu Tansey, PhD., Professor, Emory University

  1. Role of Endo-lysosomal granulins in Frontotemporal dementia and Alzheimer’s disease - Thomas Kukar, PhD; Assist. Professor, Emory University
  2. Contributions of axonal lysosome biogenesis and transport defects to Alzheimer’s disease risk - Shawn Ferguson, PhD; Assist. Professor, Yale University School of Medicine
  3. Parkin- and PINK1-mediated mitophagy dampens inflammation - Danielle Sliter, PhD; NIH/NINDS
  4. The role of LRRK2 in immune cells and inflammatory responses in Parkinson's disease - Malu Tansey, PhD; Professor, Emory University

Raincross A/D

4:00 pm - 5:30 pm

C07: The (Cyto)Skeleton in the Closet: Revealing Cytoskeletal Contributions to Neuronal Disease and Degeneration

Chair: Jeff Moore, PhD, University of Colorado Anschutz Medical Campus
Co-Chair: Jayne Aiken; University of Colorado Anschutz Medical Campus

  1. A new mouse model for SPAST-based Hereditary Spastic Paraplegia reveals the importance of a toxic gain-of-function mechanism - Peter Baas, PhD; Professor, Drexel University College of Medicine
  2. Actin cytoskeleton in stroke & degeneration - Shelley Halpain, PhD; Professor, University of California, San Diego
  3. The contribution of cytoskeletal defects to ALS pathogenesis - John Landers, PhD; Professor, University of Massachusetts Medical School
  4. Compromised Tuba1a function causes neurodegeneration through a post developmental mechanism - Emily Bates, PhD; Assistant Professor, University of Colorado School of Medicine

Raincross B/E

4:00 pm - 5:30 pm

C08:  Signaling Pathway Dysfunction in Neurologic Diseases

Chair: Etty (Tika) Benveniste, PhD, University of Alabama at Birmingham
Co-Chair: Roberta Brambilla, PhD., University of Miami Miller SOM

  1. PERK Signaling in Astrocytes Regulates Neuroinflammation - Gordon Meares, PhD; Assist. Professor, West Virginia University
  2. Opposing Functions of Microglial and Macrophagic TNFR2 in EAE - Roberta Brambilla, PhD; Assist. Professor, University of Miami Miller SOM
  3. TGF-beta Modulates Microglial Phenotype after Intracerebral Hemorrhage - Lauren Sansing, MD; Assoc. Professor, Yale University
  4. CK2 Signaling in T-cells Influences EAE Disease Severity - Etty (Tika) Benveniste, PhD; Professor, University of Alabama at Birmingham

Raincross C/F 

5:30 pm - 7:00 pm

Poster Session II - Authors Present                                  
Wine & Cheese Served

Exhibit Hall C/D

7:00 pm - 10:00 pm

Neurochemical Research Editorial Board Meeting

Room 8

WEDNESDAY, MARCH 28

7:00 am - 5:00 pm
yin  and  yang  ASN Registration Desk Open  
Concourse 201
8:15 am - 8:30 am

General Session - Opening Remarks

ASN Neuro Award Sanofi AwardBiolegend Award

Raincross Ballroom  

8:30 am - 9:30 am

Presidential Lecture 04: Environment Matters: Microglial Function and Dysfunction in a Changing World

BilboStaci2

Staci Bilbo, PhD - Harvard University

Raincross Ballroom  

9:30 am - 10:00 am
Coffee Break & Visit Exhibits / Remove Posters

Exhibit Hall C/D

10:00 am - 12:00 pm

Plenary Lecture PL04: CNS Viruses: Mechanisms of Zika, HIV, and HSV Tropism and Damage

Chair: Kurt F. Hauser, PhD; Professor, Virginia Commonwealth University School of Medicine

  1. TBA - Arnold Kriegstein, MD, PhD; Professor of Neurology, University of California San Francisco
  2. Glial cells in NeuroHIV - Marcus Kaul, PhD; Associate Professor, University of California, Riverside
  3. Nuclear Neurokinin-1 Receptor Promotes Varicella Zoster Virus Spread in Human Spinal Astrocytes - Maria A. Nagel, MD; Associate Professor, University of Colorado, Denver
  4. Progressive Multifocal Leukoenephalopathy: Endemic Viruses and Lethal Brain Disease - Walter J. Atwood, PhD; Professor, Brown University

Raincross Ballroom

12:00 pm - 3:30 pm

 ASN Council Meeting II                                                  

Room 8

1:30 pm - 3:30 pm

S07: Astrocyte Heterogeneity and CNS Functions

Chair: Robyn Klein, MD, PhD; Professor, Washington University School of Medicine

  1. Diverse Astrocyte Populations - Benjamin Deneen, PhD; Assoc Professor, Baylor College of Medicine
  2. Heterogeneity in Synaptogenic Profile of Astrocytes from Different Brain Regions - Flavia Gomes, PhD; Professor, Universidade Federal de Rio de Janeiro, Brazil
  3. Astrocytes determine lesion locations during CNS autoimmunity - Jessica Williams, PhD; Assist Professor, Cleveland Clinic
  4. Astrocytes decrease adult neurogenesis during virus-induced memory dysfunction via interleukin-1 - Robyn Klein, MD, PhD; Professor, Washington University School of Medicine

Raincross A/D

1:30 pm - 3:30 pm

S08: Shaping Microglia by Their Environment: Implications for Health and Disease

Chair: Hui Zong, PhD; Assoc. Professor, University of Virginia
Co-Chair: Anna Molofsky, Assist. Prof, University of California, San Francisco

  1. Roles of Nature and Nurture in Specifying Microglia Identity and Function - Christopher Glass, PhD; Professor, University of California, San Diego
  2. Epigenetic control of regional microglia specification - Anne Schaefer, MD, PhD; Associate Professor, ICahn School of Medicine
  3. Astrocyte-encoded cues regulating microglial developmental functions - Anna Molofsky, PhD; Assistant Professor, University of California, San Francisco
  4. Microglia shaped by tumor microenvironment support tumor progression - Hui Zong, PhD; Associate Professor, University of Virginia School of Medicine

Raincross B/E 

3:30 pm - 4:00 pm
Coffee Break & Visit Exhibits

Exhibit Hall C/D

4:00 pm - 5:30 pm

Sponsored by

Avanti logo

C09: Neuropathy: Challenges and New Targets

Chair: Stefanka Spassieva, PhD, Asst. Professor, University of Kentucky

  1. Methylglyoxal requires AC1 and TRPA1 to produce painful diabetic neuropathy and spinal neuron activation - Bradley Taylor, PhD; Professor, University of Kentucky
  2. The role of Fig4 in central and peripheral nervous system myelination - Roman Giger, PhD; Professor, University of Michigan School of Medicine
  3. Wnt pathway in Schwann cells during development and following crush injury - Brian Popko, PhD; Professor, University of Chicago
  4. Deoxysphingolipids in chemotherapy-induced peripheral neuropathy - Stefanka Spassieva, PhD; Asst. Professor, University of Kentucky

Raincross A/D

 

C10: Parasites in Your Brain and the Neurological Implications 

Chair: Emma Wilson, PhD; Assoc. Professor, University of California, Riverside
Co-Chair: Ira Blader, PhD; Professor, University of Buffalo

  1. Parasite manipulation of GABA signaling - Ira Blader, PhD; Professor, University of Buffalo
  2. Regulation of GLT1 during parasite infection in the CNS - Emma Wilson, PhD; Assoc. Professor, University of California, Riverside
  3. Chronic Toxoplasma infection-induced neuroinflammation is associated with distinct alterations in the synaptic protein composition - Ildiko Dunay, PhD
  4. Understanding Toxoplasma gondii potentiation of Huntington’s disease - Jason Gigley, PhD; Assist. Professor, University of Wyoming

Raincross B/E

 

OR02: Oral Session II - Presentation of Selected Abstracts

Raincross C/F

7:30 pm - 10:30 pm

 

ASN Closing Reception / Dinner & Dancing                
Hosted by  ASN logo
All registered delegates are invited to attend the closing reception.

Raincross Ballroom  

 

 

 

YIAC - Young Investigator Workshop on Finding the Right Fit: Academia